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Who We Are
Overview

Founded in China in 2009 CanSino Biologics Inc. (CanSinoBIO) is an industry-leading biopharmaceutical company dedicated to providing global solutions for the prevention and treatment of infectious diseases through research & development manufacturing and commercialization of innovative high-quality and affordable vaccine products for human use.

CanSinoBIO has been listed on the Main Board of Hong Kong Exchange and Clearing Limited (HKEX: 6185.HK) and on the Sci-Tech Innovation Board (STAR Market, SHSE: 688185) of the Shanghai Stock Exchange, making it the first "A+H" dual-listed vaccine company in China. Currently, our marketed products include Convidecia Air® [Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation], Convidecia® [Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)], Menphecia® [Groups A and C Meningococcal Polysaccharide Conjugate Vaccine (CRM197)], Menhycia® [Group ACYW135 Meningococcal Polysaccharide Conjugate Vaccine (CRM197)], and Ad5-EBOV. At present, the Company is developing and conducting clinical trials of several products including potential best-in-class and first-in-class vaccines in China and globally innovative and potential global best-in-class vaccines. CanSinoBIO has developed five key platform technologies, including Adenovirus-based viral vector technology, Synthetic biotechnology, Protein structure design and VLP assembly, mRNA and LNP technology as well as Formulation and drug delivery technology. In addition, the Company owns a number of core intellectual property rights and proprietary technologies related to vaccine products. CanSinoBIO has established a rich portfolio of a pipeline products preventing more than ten diseases, including COVID-19, Ebola virus disease, tuberculosis, meningitis, pertussis, diphtheria, tetanus, shingles etc., and is participating in innovative R&D collaboration with multiple research institutions across the world. We have constructed large-scale manufacturing bases in Tianjin and Shanghai, with a floor area of over 100,000 square meters. Both have been designed and constructed, and are operating in accordance with international standards to manufacture multiple novel vaccines. In addition, local fill-and-finish production lines have been set up in Mexico, Pakistan, and Malaysia to establish joint manufacturing. Our full-fledged marketing and supply system that covers Asia, Latin America, Africa, and other regions ensures the rapid distribution of vaccine products worldwide. As a leader in innovative vaccine R&D, we are deeply committed to the protection of global public health through the fulfillment of our social and international responsibilities, and the development and supply of high-quality vaccine products.

Culture and Values
Mission:
To provide high-quality innovative and affordable vaccines
Vision:
Innovation for a safer world
Values:
Respect Agility Innovation Superior in quality Engagement
Milestones
2009
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  • Incorporated and registered in Tianjin, China
2011
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  • Incorporated and registered in Tianjin, China
2012
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  • Completed the construction of GMP standard pilot plant
2014
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  • Obtained CTA approval of Ad5-EBOV and initiated clinical trial
  • Filed CTA for DTcP candidates
2015
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  • Pilot facility passed European QP inspection
  • Obtained CTA approvals of MCV2 & MCV4
2016
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  • Submitted CTA of PBPV
  • Completed Ad5-EBOV phase II clinical trial in Sierra Leone
2017
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  • Obtained NDA approval of Ad5-EBOV in China
2018
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  • Obtained CTA approval of DTcP
  • Bacterial vaccine manufacturing facility comes into operation
2019
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  • Obtained CTA approval of PCV13i
  • NDA for MCV4 was granted with priority review
  • NDA for MCV2 was accepted by NMPA
  • Listed on the main board of HKEX
2020
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  • Completed Convidecia® phase II clinical trial, and launched multi-center phase I
  • Listed on the Sci-Tech Innovation Board of SSE
2021
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  • Menhycia® approved in China
  • Menphecia® approved in China
  • The Recombinant Novel Coronavirus Vaccine Convidecia® received approval in over
2022
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  • The world's first inhaled COVID-19 vaccine Convidecia Air® approved as heterolog
  • Convidecia Air® approved for Emergency Use in Morocco
  • The WHO granted the Emergency Use Listing for the Recombinant Novel Coronavirus
  • The Recombinant Novel Coronavirus vaccine Convidecia® approved as heterologous b
2023
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  • DTcP Infant vaccine entered Phase Ⅲ clinical trial
  • Bivalent COVID-19 mRNA vaccine, Tdcp Adolescent and Adult, and Tetanus vaccine approved for clinical trial
  • Initiated Phase Ⅰb clinical trial for PBPV
  • Subscription Agreement with Solution Group Berhad
  • Convidecia® registered as a pharmaceutical product in Hong Kong, and obtains Halal Decree in Indonesia
  • IM & IH of Zoster Vaccine approved for clinical trial in Canada
  • Framework Agreement with AstraZeneca on mRNA vaccine
  • Convidecia Air® approved in Indonesia
2024
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  • Grant agreement reached with the Bill & Melinda Gates Foundation for VLP-Polio and related combined vaccine project
  • VLP-Polio obtained clinical trial approval in Indonesia
  • Initiated Phase Ⅲ clinical trial for Menhycia® in Indonesia
  • Obtained clinical trial approval of the Hib Vaccine
  • Received positive preliminary results from Phase I clinical trials of the PBPV
  • Initiated Phase Ⅲ clinical trial for Absorbed Tetanus Vaccine
  • Acceptance of drug application for registration for the PCV13i
  • Initiated Phase I clinical trial for VLP-Polio in Australia
2009 2011 2012 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Management Team
Xuefeng YU, PhD
Chairman and Chief Executive Officer 

With 30+ years of experience in biotechnology R&D. Dr. Yu is responsible for overseeing strategic development, overall operations and management, and major decision-making.

Shoubai CHAO, PhD
Chief Operating Officer and Executive Director

With 30+ years of operations and management experience in biotechnology. Dr. Chao is responsible for daily operations and management as well as strategic development.

Tao ZHU, PhD
Chief Scientific Officer

With 20+ years of experience in biotechnology R&D. Dr. Zhu is responsible for leading innovative R&D of vaccines.

Jing WANG
Chief Commercial Officer and Executive Director

With 20+ years of experience in commercial operations, investment, and financing management in the pharmaceutical industry. Ms. Wang is responsible for overall commercial operations.

Scientific Advisory Board
George Siber, Co-Chair
George Siber, Co-Chair,

Dr. George Siber is an infectious disease trained physician with 40 years’ experience in developing vaccines and antibody products. Dr. George Siber was an Associate Professor of Dana Farber Cancer Institute at Harvard Medical School and Director of the Massachusetts Public Health Biologic Laboratories. Currently he is an Adjunct Professor of Medicine at Johns Hopkins Medical School.Dr. Siber served as Executive Vice President and Chief Scientific Officer of Wyeth Vaccines (Pfizer) 1996-2007, leading the development and approval of multiple childhood vaccines including Prevenar 7 and 13.Currently Dr. Siber is a Co-founder and Board Member of Affinivax and a Board Member of Genocea Biosciences and serves on multiple Scientific Advisory Boards including AdVaccine, Everest, Clover, ILiAD, Valneva, Vaxart and Vaxxinity. Dr. Siber has received multiple awards including the Albert Sabin Gold Medal in vaccinology in 2016.

Liming Li, Co-Chair
Liming Li, Co-Chair,

Prof. Liming Li is the Boya Professor and the Dean of School of Public Health and major Epidemic Prevention and Control, Peking University. The Founder Director General of Chinese Center for Disease Control and Prevention (CDC).Prof. Li has been engaged in the large population cohort study, chronic disease epidemiology, and geriatric epidemiology for a long time. Prof. Li was awarded the EISENHOWER Fellowship Award in 1997; the Johns Hopkins Society of Scholars Award in 2006; Honorary Fellow of the Faculty of Public Health of the Royal Colleges of Physicians of the United Kingdom (HonFFPH) in 2010 and Academician of International Eurasian Academy of Sciences (IEAS) in 2017.Over 450 publications in peer-reviewed journals

Luis Barreto
Luis Barreto,

Dr. Luis Barreto is the President of Dr. Luis Barreto & Associates. Dr Barreto is a member of the International Advisory Board of the McMaster/Maastricht/Manipal Global Health Program, a member of the Scientific Advisory Board for the Human Health Therapeutics Group of the National Research Council (NRC), Canada, a Senior Scientifc Advisor to Inventprise/InventVac U.S./Canada. Dr. Barreto was formerly Vice-President of Clinical, Medical and Regulatory Affairs, Vice-President of Immunization and Science Policy, and a member of the Senior Management Team at Sanofi Pasteur Canada, as well as a member of its Global Public Policy group. He spent more than 23 years in research and development, leading Phase 1-IV clinical trials, licensing and launching vaccines globally. Dr. Barreto has been/is on many volunteer boards of directors, including VIDO-InterVAC (Chair), Research Canada, March of Dimes. He has been/is on many advisory review panels for the Tri Council (CIHR, NSERC and CFI) with the government of Canada and Not for Profit organisations. He has also been member of two panels of the Council of Canadian Academies, Canada.

Pierre Van Damme
Pierre Van Damme,

Prof. Dr. Pierre Van Damme obtained his PhD in epidemiology and public health in 1994. He was for more than 35 years active in vaccine, clinical trial and infectious disease research. Since 2000 he is full professor in Vaccinology at the University of Antwerp, Faculty of Medicine and Health Sciences. Dr. Van Damme is the founder and director of the Centre for the Evaluation of Vaccination (CEV, University of Antwerp), a WHO Collaborating Centre for the control and prevention of infectious diseases in European region. Dr. Van Damme has been for more than 25 years a regular advisor for national and international organizations, including the National Immunization Technical Advisory Group, and the World Health Organization. He has been appointed as chairman of the European Technical Advisory Group of Experts on communicable diseases and vaccines for the WHO European Region (ETAGE) (2005-2015).

Shan Lu
Shan Lu,

Prof. Shan Lu is a physician scientist with research interest in novel vaccine and antibody development, an expert on vaccines for HIV, influenza, biodefense agents, and emerging infectious diseases. Dr. Lu was the past president and a current Executive Board member for the International Society for Vaccines (ISV). Prof. Lu is known as the originator of the DNA prime/protein boost approach to vaccination. He is one of the few people to have developed a candidate vaccine starting at the bench and going all the way to a clinical trial in humans.Prof. Lu is the editor-in-chief of Emerging Microbes & Infections.

David Salisbury
David Salisbury,

Prof. David Salisbury was Director of Immunisation at the Department of Health and has chaired the Strategic Advisory Group of Experts on immunisation for the World Health Organisation. He has led the introduction of a large number of new immunisation programmes and vaccines. The UK immunisation programme is one of the foremost in the world and its excellence is recognised in both developed and developing countries. He has demonstrated that the successful immunisation programmes require the collaboration of science, policy development, strategy and implementation, and whose impact has been the saving of thousands of lives. He is the Chair of the Jenner Vaccine Foundation and is a Board Trustee of the Sabin Vaccine Institute. He is also Chair of the WHO Global Commission for Certification of Poliomyelitis Eradication.

 

Jingren Zhang
Jingren Zhang,

Prof. Jingren Zhang is the professor of Medical School in Tsinghua university, mainly focusing on the molecular mechanism of acute pneumonia and related diseases. Dr. Zhang obtained his doctorate in microbiology from the University of Texas Health Science Center-Houston in 1997. During 1998 to 2000, he worked as a postdoctoral fellow in the department of infectious diseases at St. Jude Children’s Research Hospital. Dr. Zhang worked in the China Agricultural University, associate professor from Albany Medical College, US and a visiting professor by institute of microbiology, Chinese Academy of Sciences.

Compliance Management

In the process of building an excellent reputation, Cancino Bio always adheres to the belief of "compliance with the law".

Integrity, ethics and compliance are key to the sustainable development and success of Cancino Bio today and in the future to maintain public trust, respect and recognition.

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